Diagnosis and management of giant cell arteritis and polymyalgia rheumatica: challenges, controversies and practical tips
Identifieur interne : 002873 ( Main/Exploration ); précédent : 002872; suivant : 002874Diagnosis and management of giant cell arteritis and polymyalgia rheumatica: challenges, controversies and practical tips
Auteurs : Sarah Louise Mackie [Royaume-Uni] ; Colin Thomas Pease [Royaume-Uni]Source :
- Postgraduate Medical Journal [ 0032-5473 ] ; 2013-05.
English descriptors
- Teeft :
- Adverse effects, Alternative explanations, American college, Aortic, Aortic dissection, Arteritis, Artery biopsy, Arthritis, Arthritis rheum, Biopsy, Biopsy positivity, Case series, Cimmino, Claudication, Clin, Clinical features, Clinical practice, Clinical utility, Cranial, Disease activity, Erythrocyte, Erythrocyte sedimentation rate, Giant cell, Giant cell arteritis, Glucocorticoid, Glucocorticoid dose, Glucocorticoid therapy, Glucocorticoid treatment, Imaging, Initial treatment, Ischaemic, Ischaemic complications, Ischaemic features, Mackie, Magnetic resonance imaging, Medical emergency, Musculoskeletal, Ndings, Normal markers, Ophthalmological evaluation, Original diagnosis, Other conditions, Polymyalgia, Polymyalgia rheumatica, Positive biopsy, Postgrad, Prednisolone, Prospective study, Randomized, Relapse, Retrospective study, Rheum, Rheumatica, Rheumatoid arthritis, Rheumatol, Rheumatol suppl, Rheumatology, Rheumatology criteria, Risk factors, Salvarani, Symptom, Temporal, Temporal arteries, Temporal arteritis, Temporal artery, Temporal artery biopsy, Temporal artery ultrasound, Ultrasound, Vascular imaging, Vasculitis, Visual loss, Visual manifestations, Visual symptoms, Weight loss.
Abstract
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory rheumatic diseases that may present to a variety of disciplines and specialities. The mainstay of treatment is glucocorticoids (steroids); together PMR and GCA now represent one of the most common reasons for medium-to-high dose, long-term glucocorticoid treatment in primary care. However, adverse effects of glucocorticoids are common in these patients. Management of both diseases involves balancing the symptoms and risks of the disease against the adverse effects and risks of glucocorticoids. The crucial first step in management is to make a firm, well-documented diagnosis, since once glucocorticoids are started they can mask the symptoms of a number of other diseases. Diagnosis however can be challenging and there are still substantial gaps in the evidence for treatment.
Url:
DOI: 10.1136/postgradmedj-2012-131400
Affiliations:
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criteria</term><term>Risk factors</term><term>Salvarani</term><term>Symptom</term><term>Temporal</term><term>Temporal arteries</term><term>Temporal arteritis</term><term>Temporal artery</term><term>Temporal artery biopsy</term><term>Temporal artery ultrasound</term><term>Ultrasound</term><term>Vascular imaging</term><term>Vasculitis</term><term>Visual loss</term><term>Visual manifestations</term><term>Visual symptoms</term><term>Weight loss</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory rheumatic diseases that may present to a variety of disciplines and specialities. The mainstay of treatment is glucocorticoids (steroids); together PMR and GCA now represent one of the most common reasons for medium-to-high dose, long-term glucocorticoid treatment in primary care. However, adverse effects of glucocorticoids are common in these patients. Management of both diseases involves balancing the symptoms and risks of the disease against the adverse effects and risks of glucocorticoids. The crucial first step in management is to make a firm, well-documented diagnosis, since once glucocorticoids are started they can mask the symptoms of a number of other diseases. Diagnosis however can be challenging and there are still substantial gaps in the evidence for treatment.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Yorkshire-et-Humber</li></region><settlement><li>Leeds</li></settlement><orgName><li>Université de Leeds</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Mackie, Sarah Louise" sort="Mackie, Sarah Louise" uniqKey="Mackie S" first="Sarah Louise" last="Mackie">Sarah Louise Mackie</name></region><name sortKey="Pease, Colin Thomas" sort="Pease, Colin Thomas" uniqKey="Pease C" first="Colin Thomas" last="Pease">Colin Thomas Pease</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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